Omeros

Omeros Unlocks 46 Orphan G Protein-Coupled Receptors

According to the company, the figure equals the number GPCRs targeted by more than 30 percent of currently marketed drugs.

Omeros Corp. today announced that it has identified compounds that functionally interact with each of four additional orphan G protein-coupled receptors (GPCRs). Without compounds that functionally interact with orphan GPCRs, developing drugs targeting those receptors is extremely difficult. Omeros has now unlocked 46 Class A orphan GPCRs, representing almost 60 percent of these targets and equaling the number of GPCRs that are targeted by over 30 percent of all marketed drugs.

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Omeros Announces Unlocking of Class A Orphan GPCRs

The unlocking of the compounds, according to the company, could lead to new treatments for autism, osteoarthritis neuropsychiatric disorders.

Omeros Corp. announced that it has identified compounds that functionally interact with each of five additional orphan G protein-coupled receptors (GPCRs). Without compounds that functionally interact with orphan GPCRs, developing drugs targeting those receptors is extremely difficult. Omeros has now unlocked 42 Class A orphan GPCRs, representing over half of these targets. There are approximately 120 orphan GPCRs and Omeros expects to unlock a large percentage of them, focusing first on Class A orphans.

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