Pfizer Brings Frequent Heartburn Relief Over-the-Counter with New Nexium� 24HR

Pfizer Inc. (NYSE: PFE) today announced the introduction in the U.S. of
over-the-counter (OTC) Nexium 24HR, making The Purple Pill
available for the treatment of frequent heartburn (two or more days a
week) in adults (18 years and older). Heartburn affects more than 60
million men and women in the United States at least once a month with 15
million Americans suffering from it daily.

Pfizer acquired exclusive global OTC rights to NEXIUM, one
of the largest selling prescription brands in the U.S., from AstraZeneca
in August 2012. Nexium 24HR was approved by the Food and Drug
Administration on March 28, and received three year market exclusivity.
Switching medicines from prescription to non-prescription status
improves consumer access to affordable healthcare options, empowers
people to take charge of their health, and is an important strategy for
Pfizer. The launch of Nexium 24HR makes Pfizer a leading player in all
four of the largest OTC categories – pain management, dietary
supplements, respiratory and, now, digestive.

“The addition of Nexium 24HR to our portfolio enhances our ability to
help consumers better manage their health,” said Paul Sturman, President
and General Manager, Pfizer Consumer Healthcare. “Nexium 24HR creates a
new option for treating frequent heartburn with the confidence of a
brand that consumers and healthcare providers know and trust. The OTC
availability of Nexium 24HR in the U.S. marks the first step in our
efforts to build a strong, global position in digestive health with this
powerful brand.”

Nexium 24HR has been available in the U.S. for preorder at
since April 15,2014, and, within 72 hours, Nexium 24HR will
be available nationwide at most retailer outlets.

“Switching a brand with this kind of loyalty and equity is a tremendous
business opportunity, and we have a critical responsibility to our
partners, to our retail customers, to healthcare providers and most
importantly, to consumers,” said T.J. Higgins, North American President,
Pfizer Consumer Healthcare. “Nexium 24HR protects people from frequent
heartburn, and also from the fear and hesitation that heartburn causes.”

Nexium 24HR works differently than other OTC medications for heartburn
such as antacids and histamine blockers. Specifically, Nexium 24HR is a
proton pump inhibitor (PPI), which means it stops acid production at the
source, by blocking the pumps that release acid into the stomach. In
fact, PPIs like Nexium 24HR are the only FDA-approved medications for
over-the-counter treatment of frequent heartburn.

“I, along with many of my colleagues, have come to trust The Purple Pill
as the number one prescribed acid blocker brand,” said David A. Johnson,
MD, MACG, FASGE, Professor of Medicine and Chief of Gastroenterology
Eastern VA Medical School Norfolk VA. “The availability of Nexium 24HR
represents an important development in access to the medication at a
time when people are in need of a short term course of therapy for
effective self-care solutions. And with 15 million Americans suffering
from heartburn daily, making NEXIUM available without
prescription helps to fill a crucially important unmet need.”

Nexium 24HR is to be used once a day (every 24 hours), every day for 14
days and may take 1-4 days for full effect. The 14-day course can be
repeated every 4 months. People should not take more than 1 capsule of
Nexium 24HR a day, unless directed by a doctor.

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Nexium 24HR brings NEXIUM, the #1
doctor-prescribed acid-reducer brand, over-the-counter to treat frequent
heartburn. The active ingredient in Nexium 24HR is
esomeprazole 20 mg, which is a part of a group of medications called
proton pump inhibitors or PPIs. Nexium 24HR works by blocking acid at
the source, giving 24 hours of protection from frequent heartburn when
used as directed. Nexium 24HR represents an important development in
increased access to The Purple Pill by giving people a new
way to access a trusted, effective product. If you have questions about
whether Nexium 24HR is right for you, speak with your healthcare
provider prior to taking the product. For more information, visit

At Pfizer, we apply science and our global resources to bring therapies
to people that extend and significantly improve their lives. We strive
to set the standard for quality, safety and value in the discovery,
development and manufacture of health care products. Our global
portfolio includes medicines and vaccines as well as many of the world's
best-known consumer health care products. Every day, Pfizer colleagues
work across developed and emerging markets to advance wellness,
prevention, treatments and cures that challenge the most feared diseases
of our time. Consistent with our responsibility as one of the world's
premier innovative biopharmaceutical companies, we collaborate with
health care providers, governments and local communities to support and
expand access to reliable, affordable health care around the world. For
more than 150 years, Pfizer has worked to make a difference for all who
rely on us. To learn more, please visit us at

This press release has an accompanying Smart Marketing Page providing
further details about the organization, products and services introduced
above. You can access the Smart Marketing Page via the following link:

Smoking and Your Digestive System. 1999. National Digestive
Diseases Information Clearinghouse. NIH Publication No.99-949.

Pfizer Inc.Media Contact:Sally Beatty, 212-733-6566orInvestor
Contact:Ryan Crowe, 212-733-8160

Source: Pfizer Inc.