PRODUCT UPDATE Protective and Convenient Parenterals
Parenteral packaging helps reduce needle-stick injuries and contamination risks.
A 12-cm3 syringe features a double O-ring installed at the end of the plunger to prevent the contents from escaping out the back. This helps end-users use every cubic centimeter and avoid potentially messy handling in the process. The syringes are available in clear or white, and in quantities of 1000 pieces or more. The company also offers imprinting services. Mil-Comm Products Co., East Rutherford, NJ; 201/935-8561; www.milcomm.com.
Seals, Stoppers, and Syringe Plungers
A company specializes in rubber compounds to produce seals for inhalants and injectable products, and rubber stoppers for general pharmaceutical liquid packaging. The rubber compounding department is equipped with state-of-the-art mixing equipment to provide microscopic dispersion of raw materials. This procedure assures reproducibility of the rubber compounds' established physical and chemical properties, batch after batch. New rubber compounds are made without plasticizers for extended shelf life of injectables and inhalants where low extraction of primary packaging is vital. Tekni-Plex, Medical Rubber Div., Somerville, NJ; 908/722-4800; www.tekni-plex.com.
A company develops custom-tailored injection systems, such as prefillable syringes and cartridges, as well as plastic bottles, complete with auxillary components, closures, transport systems, and packaging materials. Aseptic manufacturing qualification and validation is conducted in accordance with FDA, cGMP, and EC guidelines. The company designs and optimizes prototype and product tools for the fabrication of single components and assembly parts. All technologies used are transferable to existing injection systems, production processes, buildings, and equipment. Vetter Pharma Turm, Yardley, PA; 215/321-6930; www.pharmaturm.com.
For drugs that are applied topically, a single-use dispensing system offers package integrity, safety, and single-handed ease of use. This glass-free system comprises a one-piece molded polyethylene or polypropylene unit that remains intact and sealed until activated by the user. Activation is accomplished with a gentle squeeze of the package, which breaks an inner plastic membrane that seals in the contents prior to use. Another gentle squeeze then dispenses the product. The plastic ampule package is manufactured in a variety of sizes and styles ranging from dropper tips to swabs to custom dispensers. In addition to producing, filling, and sealing the ampules to customer specifications, the company also provides printing and secondary packaging services, including date and lot code stamping for direct sale, resale, and point of purchase. James Alexander, Blairstown, NJ; 908/362-9266; www.james-alexander.com.