Capsule Fillers
Published: September 30th, 2009
Compact Capsule Filler
A new fully automatic capsule filler is modular and compact. The Labby can operate in either continuous or intermittent mode, depending on the type of dosing unit installed. Its small footprint makes it a solid choice for R&D laboratories, clinical trials, small-batch outputs, and special productions, according to the company. The capsule filler can fill up to 3500 capsules per hour and is designed to handle a variety of powders, including API without excipients or bulking agents. According to the manufacturer, it is ideal for dosing weights ranging from 0.5 to 20 mg, without compaction and with 100% net dosage weight checking. The Labby can be used to dose powder with dosators; low dosages of powder to be inhaled without compaction with dosators; microsized dosages of powder without compaction using vibration; powder with tamping pin; pellets; tablets; universal tablet feeder; microtablets using counting; capsule into capsule; and liquids. The unit comes with a 100% microweighing control system of the net product weight and control system accuracy of ±0.1 mg of the net weight, depending on the target weight and product characteristics. MG America, Fairfield, NJ; 973/808-8185; www.mgamerica.com.
Natural Capsule Colorants
A line of natural colorants for capsules is available in the Americas. The colors include plum punch, ocean blue, candy apple, and kiwi pearl. Natural ingredients such as caramel, riboflavin, carmine, and spirulina are used to create the initial color spectrum. Spirulina is sourced from the blue-green algae plant, while caramel is brownish and produced through the heat-treatment of corn syrup or sugar. Riboflavin is an orange-yellow compound in the vitamin B complex that naturally occurs in foods such as vegetables and milk. The colors can be made opaque when combined with titanium dioxide, a naturally occurring mineral. The colors can also be given a pearled effect when combined with all-natural Candurin pigment. Capsugel, Peapack, NJ; 908/901-8000; www.capsugel.com.
Versatile Capsule Filler
A fully automated capsule-filling machine can handle various types of dosage forms. The LIQFILsuper F-40 maintains high fill-weight accuracy to ensure precision. During capsule rectification, capsule defects such as deformation, scratching, and peeling of imprinted characters do not occur, since no external pressures are applied to capsules, according to the company. An O-ring acts as a shock absorber when receiving the end of the capsule body, thus preventing cracking of the capsule. A disk feeder cuts down and supplies fill without stirring, making it possible to supply fixed quantities without changing particle distribution. Capsules are filled directly into the body by a mechanical vibration filling method. After the unit presses in equal density, the fixed quantity is pushed upward from the bottom, the weight is adjusted by scraping the surplus powder out, and the capsule is then joined. The filled capsule body is lifted upward by the pusher and joined with the cap through the joining block. Joined capsules are lifted over the cap disc by a pusher and then discharged. The F-40 is compact, measuring 30.7 × 26.8 in. and operates at 40,000 capsules per hour. The Qualicaps Group, Whitsett, NC; 336/449-3900; www.qualicaps.com.
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